Which method is typically used to calculate mass percent in a compound?

The calculation of mass percent in a compound focuses on determining the contribution of each element’s mass relative to the total mass of the compound. The mass percent is defined as the mass of a particular component (like an element in a compound) divided by the total mass of the compound, multiplied by 100. This ratio indicates how much of the compound's mass is made up by that specific element, expressed as a percentage.

In this context, considering the choice indicates the mass of the solute or solvent does not apply to the definition of mass percent for a compound. Mass percent calculations specifically look at the mass of the compound in its entirety, as this is fundamental for understanding the composition of chemical substances. Thus, the approach focusing on the mass of the solute compared to the total mass of the compound accurately reflects the method for calculating mass percent, confirming that this option is indeed the correct approach.