What type of drugs are iproniazid and phenelzine?

Iproniazid and phenelzine are classified as antidepressants, specifically within the category of monoamine oxidase inhibitors (MAOIs). These drugs are designed to treat depression by inhibiting the activity of the monoamine oxidase enzyme, which is responsible for breaking down neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. By blocking this enzyme, MAOIs increase the levels of these neurotransmitters, which can help improve mood and alleviate depressive symptoms.

Given this mechanism of action, iproniazid and phenelzine are utilized in clinical settings to address various mood disorders. They are especially effective in cases where other antidepressants have not provided sufficient relief. Their identification as antidepressants emphasizes their role in mental health treatment rather than as antihistamines, stimulants, or tranquilizers, which target different physiological pathways or conditions.