What can occur from the consumption of poisonous doses of narcotic analgesics?

The consumption of poisonous doses of narcotic analgesics can lead to stupor and coma due to their central nervous system depressant effects. Narcotic analgesics, such as opioids, interact with specific receptors in the brain that modulate pain perception and can significantly depress respiratory function and consciousness at high doses. This exacerbated effect can result in a state of stupor, characterized by reduced responsiveness and awareness, which can progress to coma if the dose is sufficiently high.

This severe reaction stems from the pharmacological action of these substances, which can inhibit the neural pathways that control vital bodily functions, thus leading to a diminished state of consciousness. The other options, such as stomach upset, mild headaches, or skin rashes, are generally associated with lesser effects or side effects of narcotic analgesics rather than the acute lethal effects resulting from overdose.